Invitrogen™ ORAI2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565926

Catalog No. PIPA565926

Description

Immunogen sequence: MSAELNVPIDP SAPACPEPGH KGMDYRDWVR RSYLELVTSN HHSVQALSW Highest antigen sequence identity to the following orthologs - mouse 98%, rat 98%.

Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1.

Specifications

• Antigen: ORAI2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ORAI2
• Gene Alias: A730041O15Rik; C7orf19; calcium release-activated calcium channel 2; calcium release-activated calcium modulator 2 protein; CAP-binding protein complex interacting protein 2; CAP-binding protein complex-interacting protein 2; CBCIP2; H_NH0514P08.8; MEM142B; ORAI calcium release-activated calcium modulator 2; ORAI2; PP1729; Protein orai-2; putative protein ORAI2-2; RGD1310213; TMEM142B; Transmembrane protein 142B
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 80228
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96SN7
• Gene Symbols: ORAI2
• Immunogen: Recombinant Human ORAI2. Recombinant protein control fragment (Product #RP-106605).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG