Invitrogen™ ORAI3 Monoclonal Antibody (1B4F1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515779

Catalog No. PIMA515779

Description

A suggested positive control is rat lung tissue lysate.

ORAI3 is a protein coding gene that is involved in calcium signaling and regulation of calcium homeostasis. It is a member of the ORAI family of proteins that form calcium release-activated calcium (CRAC) channels in the plasma membrane of cells. These channels are activated by depletion of calcium from the endoplasmic reticulum, leading to an influx of calcium ions into the cytoplasm. ORAI3 has been implicated in a variety of physiological processes, including T-cell activation, muscle contraction, and neurotransmitter release. Dysregulation of ORAI3 expression or function has been associated with various diseases, including immune disorders, cancer, and cardiovascular disease.

Specifications

• Antigen: ORAI3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q6AXR8, Q9BRQ5
• Gene Symbols: ORAI3
• Immunogen: A 19 amino acid peptide from near the carboxy terminus of human ORAI3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot
• Clone: 1B4F1
• Conjugate: Unconjugated
• Gene: ORAI3
• Gene Alias: 9930124N15; BC061259; calcium release-activated calcium channel 3; calcium release-activated calcium modulator 3 protein; ORAI calcium release-activated calcium modulator 3; ORAI3; Protein orai-3; RGD1306538; Tmem142c; Transmembrane protein 142C
• Host Species: Mouse
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 309000, 93129
• Content And Storage: -20°C
• Form: Liquid