Invitrogen™ ORC3 Monoclonal Antibody (1D6)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA517024

Catalog No. PIMA517024

Description

MA5-17024 reacts with ORC3 in human samples. MA5-17024 has been successfully used in immunoprecipitation and Western blot applications. The MA5-17024 immunogen is ORC3 (hsORC) produced in P3-x63Ag.8.653 cells.

Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.

Specifications

• Antigen: ORC3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q9UBD5
• Gene Symbols: ORC3
• Immunogen: Full length human ORC3L protein.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunoprecipitation, Western Blot
• Clone: 1D6
• Conjugate: Unconjugated
• Gene: ORC3
• Gene Alias: homolog of latheo, Drosophila; IMAGE50150; LAT; LATHEO; Orc3; ORC3L; origin of replication 3 homolog; origin recognition complex subunit 3; Origin recognition complex subunit Latheo; origin recognition complex, subunit 3; origin recognition complex, subunit 3 honolog; origin recognition complex, subunit 3-like; OTTHUMP00000040611; RP3-486L4.1
• Host Species: Rat
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 23595
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid