Invitrogen™ ORC3 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA517949

Catalog No. PIPA517949

Description

This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.

Specifications

• Antigen: ORC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ORC3
• Gene Alias: homolog of latheo, Drosophila; IMAGE50150; LAT; LATHEO; Orc3; ORC3L; origin of replication 3 homolog; origin recognition complex subunit 3; Origin recognition complex subunit Latheo; origin recognition complex, subunit 3; origin recognition complex, subunit 3 honolog; origin recognition complex, subunit 3-like; OTTHUMP00000040611; RP3-486L4.1
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 23595
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9UBD5
• Gene Symbols: ORC3
• Immunogen: Synthetic peptide sequence (QKTDHVARLTWGGC) corresponding to the C-terminus amino acids of ORC3L (aa 698-711).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG