Invitrogen™ ORC4 Monoclonal Antibody (2A8)

Catalog No.	Quantity
PIMA519508	100 μg

Catalog No. PIMA519508 Supplier Invitrogen™ Supplier No. MA519508

Description

Mouse Monoclonal Antibody

Peptide Sequence: MSSRKSKSNS LIHTECLSQV QRILRERFCR QSPHSNLFGV QVQYKHLSEL LKRTALHGES NSVLIIGPRG SGKTMLISHA LKELMEIEEV SENVLQVHLN GLLQINDKIA LKEITRQLNL ENVVGDKVFG SFAENLSFLL EALKKGDRTS SCPVIFILDE FDLFAHHKNQ TLLYNLFDIS QSAQTPIAVI GLTCRLDILE LLEKRVKSRF SHRQIHLMNS FGFPQYVKIF KEQLSLPAEF PDKVFAEK.

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.

Specifications

• Antigen: ORC4
• Applications: ELISA, Immunocytochemistry
• Classification: Monoclonal
• Clone: 2A8
• Concentration: 0.2-1.0 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative; pH 7.4
• Gene: ORC4
• Gene Accession No.: O43929
• Gene Alias: HSORC4; mMmORC4; Orc4; ORC4L; Orc4P; Origin recognition complex subunit 4; origin recognition complex, subunit 4; origin recognition complex, subunit 4 homolog; origin recognition complex, subunit 4-like
• Gene Symbols: ORC4
• Host Species: Mouse
• Immunogen: orc4 (AAH05388, 1 a.a. ~ 248 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5000
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b κ