Invitrogen™ ORC6 Monoclonal Antibody (3A4)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA517022

Catalog No. PIMA517022

Description

MA5-17022 reacts with ORC6 in human samples. MA5-17022 has been successfully used in ChIP, immunoprecipitation and Western blot applications. The MA5-17022 immunogen is ORC6 (hsORC) produced in P3-x63Ag.8.653 cells.

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.

Specifications

• Antigen: ORC6
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q9Y5N6
• Gene Symbols: Orc6
• Immunogen: Full length protein (Human): ORC6L.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: ChIP Assay, Immunoprecipitation, Western Blot
• Clone: 3A4
• Conjugate: Unconjugated
• Gene: Orc6
• Gene Alias: 6720420I10Rik; ORC 6; ORC6; ORC6L; origin recognition complex subunit 6; origin recognition complex, subunit 6; origin recognition complex, subunit 6-like
• Host Species: Rat
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 23594
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid