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Invitrogen™ ORC6 Monoclonal Antibody (3A4)
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Catalog No. PIMA517022
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50 μL
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Catalog No. Quantity
PIMA517022 50 μL
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Catalog No. PIMA517022 Supplier Invitrogen™ Supplier No. MA517022
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Description

Rat Monoclonal Antibody

MA5-17022 reacts with ORC6 in human samples. MA5-17022 has been successfully used in ChIP, immunoprecipitation and Western blot applications. The MA5-17022 immunogen is ORC6 (hsORC) produced in P3-x63Ag.8.653 cells.

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ORC6
Applications ChIP Assay, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 3A4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene Orc6
Gene Accession No. Q9Y5N6
Gene Alias 6720420I10Rik; ORC 6; ORC6; ORC6L; origin recognition complex subunit 6; origin recognition complex, subunit 6; origin recognition complex, subunit 6-like
Gene Symbols Orc6
Host Species Rat
Immunogen Full length protein (Human): ORC6L.
Purification Method Protein G
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23594
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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