Invitrogen™ ORC6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103509

Catalog No. PIPA5103509

Description

Antibody detects endogenous levels of total ORC6L.

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.

Specifications

• Antigen: ORC6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Orc6
• Gene Alias: 6720420I10Rik; ORC 6; ORC6; ORC6L; origin recognition complex subunit 6; origin recognition complex, subunit 6; origin recognition complex, subunit 6-like
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23594, 56452
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9WUJ8, Q9Y5N6
• Gene Symbols: Orc6
• Immunogen: A synthesized peptide derived from human ORC6(Accession Q9Y5N6), corresponding to amino acid residues R200-T250.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG