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Invitrogen™ Orexin A Polyclonal Antibody
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Catalog No. PA185744
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PA185744 1 mL
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Catalog No. PA185744 Supplier Invitrogen™ Supplier No. PA185744
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Description

Sheep Polyclonal Antibody

Predicted to react with bovine, chimpanzee, dog, horse, mouse, pig, rabbit, rat and rhesus monkey based on sequence homology. Hypothalamus tissue can be used as a positive control. Sheep anti Human orexin A antibody recognizes human orexin A, an excitatory neuropeptide linked to alertness and wakefulness in humans.

This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Orexin A
Applications ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene HCRT
Gene Accession No. O43612
Gene Alias HCRT; Hcrt1; Hcrt2; Hypocretin; Hypocretin (orexin) neuropeptide; hypocretin neuropeptide precursor; hypocretin-1; Hypocretin-2; NRCLP1; orexin; orexin A; orexin B; orexin-A; Orexin-B; ORX; OX; PPORX; PPOX; prepro-orexin
Gene Symbols HCRT
Host Species Sheep
Immunogen Synthetic peptide corresponding to amino acids P(2) L P D C C R Q K T C S C(14) of human orexin A conjugated to KLH.
Purification Method Affinity chromatography
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3060
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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