Invitrogen™ Orexin A Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA185744

Catalog No. PA185744

Description

Predicted to react with bovine, chimpanzee, dog, horse, mouse, pig, rabbit, rat and rhesus monkey based on sequence homology. Hypothalamus tissue can be used as a positive control. Sheep anti Human orexin A antibody recognizes human orexin A, an excitatory neuropeptide linked to alertness and wakefulness in humans.

This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.

Specifications

• Antigen: Orexin A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HCRT
• Gene Alias: HCRT; Hcrt1; Hcrt2; Hypocretin; Hypocretin (orexin) neuropeptide; hypocretin neuropeptide precursor; hypocretin-1; Hypocretin-2; NRCLP1; orexin; orexin A; orexin B; orexin-A; Orexin-B; ORX; OX; PPORX; PPOX; prepro-orexin
• Host Species: Sheep
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3060
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
• Concentration: 5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Gene Accession No.: O43612
• Gene Symbols: HCRT
• Immunogen: Synthetic peptide corresponding to amino acids P(2) L P D C C R Q K T C S C(14) of human orexin A conjugated to KLH.
• Quantity: 1 mL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG