Orexin Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA5121242

Catalog No. PIPA5121242

Description

Positive test controls include: U-251MG, Rat thymus. The target is usually found in the following locations: Cell junction, Cytoplasmic vesicle, Rough endoplasmic reticulum, synapse. Immunogen sequence: QPLPDCCRQK TCSCRLYELL HGAGNHAAGI LTL

Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity.

Specifications

• Antigen: Orexin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HCRT
• Gene Alias: HCRT; Hcrt1; Hcrt2; Hypocretin; hypocretin (orexin) neuropeptide; hypocretin neuropeptide precursor; Hypocretin-1; Hypocretin-2; NRCLP1; Orexin; orexin A; orexin B; Orexin-A; Orexin-B; OX; PPORX; Ppox; prepro-orexin
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15171, 25723, 3060
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1.26 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: O43612, O55232, O55241
• Gene Symbols: HCRT
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 34-66 of human HCRT (NP_0015151)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG