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  6. Org 25543 hydrochloride, Tocris Bioscience™

Org 25543 hydrochloride, Tocris Bioscience™
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Catalog No. 478250
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective GlyT2 inhibitor

Potent and selective glycine transporter type 2 (GlyT2) inhibitor (IC50 = 16 nM for hGlyT2). Displays no activity at GlyT1 or 56 other common biological targets (≥ 100 μM), in a glycine uptake assay in CHO cells. Ameliorates mechanical allodynia after partial sciatic nerve ligation injury in mice.

Chemical Identifiers

CAS 495076-64-7
Molecular Formula C24H33ClN2O4
Molecular Weight (g/mol) 448.988
InChI Key NIPQJILJYQVZJR-UHFFFAOYSA-N
Synonym org 25543 hydrochloride, 4-benzyloxy-n-1-dimethylamino cyclopentyl methyl-3,5-dimethoxybenzamide hydrochloride, n-1-dimethylamino cyclopentyl methyl-3,5-dimethoxy-4-phenylmethoxy benzamide hydrochloride
PubChem CID 10095215
IUPAC Name N-[[1-(dimethylamino)cyclopentyl]methyl]-3,5-dimethoxy-4-phenylmethoxybenzamide;hydrochloride
SMILES CN(C)C1(CCCC1)CNC(=O)C2=CC(=C(C(=C2)OC)OCC3=CC=CC=C3)OC.Cl

Specifications

Quantity 50 mg
Formula Weight 448.98
Percent Purity >99%
Chemical Name or Material Org 25543 hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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