ORM2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-6962	Proteintech Group Inc 111991AP150UL	150 μL

Description

This antibody can recognize both ORM1 and ORM2.

AGP (a 1-acid Glycoprotein) is an acute phase plasma protein synthesized by the liver. It functions to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, it also mediates the extravasation of cells during infection and inflammation. Expression of AGP is induced by acute-phase stimulatory agents such as bacterial lipopolysaccharides. AGP has a high affinity, low capacity binding for basic drugs at physiological pH. In human plasma, AGP is found at levels of 0.5-1.4 mg/ml, though this is elevated during acute inflammation, and, as a result, levels of this protein can be used to diagnose inflammatory conditions. Multiple AGP genes exist, including AGP-1, AGP-2, AGP-3 and AGP-8. AGP-1 and AGP-2 contain five and six potential N-glycosylation sites, respectively. Abnormal expression of the APG-1 gene is linked to sarcoidosis and other immunogenetic diseases, while mutations in the APG-2 gene are associated with different types of carcinomas.

Specifications

• Antigen: ORM2
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: P07361, P19652
• Gene ID (Entrez): 18406, 5005
• Immunogen: ORM2 Fusion Protein Ag1667
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ORM2

• Concentration: 0.45 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: AGP 2, AGP B, AGP B′, AGP2, Alpha 1 acid glycoprotein 2, OMD 2, ORM2, orosomucoid 2
• Gene Symbols: Orm2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody