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Invitrogen™ ORMDL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521146

Catalog No. PIPA521146


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Description

Description

A suggested positive control is SK-N-SH cell lysate. PA5-21146 can be used with blocking peptide PEP-1260.

The ORMDL (ORM1-like) family of proteins consist of ORMDL1, ORMDL2 and ORMDL3 that may play roles in -gamma-secretase complex maturation. Localized to the membrane of the endoplasmic reticulum, ORMDLs are widely expressed and are implicated in the expression of Presenilin (PSI) which is involved in Alzheimer's disease (AD). Expression of ORMDL1 is down-regulated in PSI mutations, suggesting a possible role as a therapeutic target for AD. ORMDLs have recently been identified as a potential risk factor for childhood asthma.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ORMDL1
Polyclonal
Unconjugated
ORMDL1
Adoplin-1; C730042F17Rik; HSPC202; ORM1-like 1; ORM1-like 1 (S. cerevisiae); ORM1-like protein 1; ORMDL sphingolipid biosynthesis regulator 1; ORMDL1
Rabbit
Antigen Affinity Chromatography
RUO
100188936, 227102, 94101
4°C
Liquid
Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q921I0, Q9P0S3
ORMDL1
A 16 amino acid peptide of human ORMDL1.
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG
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