Ornithine Decarboxylase Mouse anti-Human, Rat, Alexa Fluor 350, Clone: ODC1/485, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP234700AF350
DescriptionOrnithine Decarboxylase Monoclonal antibody specifically detects Ornithine Decarboxylase in Human, Rat samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen).
|Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen|
|Recombinant human ODC-1 protein|
|Protein A purified|
|Cell Cycle and Replication|
|ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot|
|Alexa Fluor™ 350|
|50 mM sodium borate with 0.05% sodium azide|
|ODCEC 184.108.40.206, ornithine decarboxylase, ornithine decarboxylase 1|
|Store at 4°C in the dark.|
|Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.|
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