Orosomucoid 2 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS9915R

Catalog No. 50-198-9448

Description

AGP (a 1-acid Glycoprotein) is an acute phase plasma protein synthesized by the liver. It functions to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, it also mediates the extravasation of cells during infection and inflammation. Expression of AGP is induced by acute-phase stimulatory agents such as bacterial lipopolysaccharides. AGP has a high affinity, low capacity binding for basic drugs at physiological pH. In human plasma, AGP is found at levels of 0.5-1.4 mg/ml, though this is elevated during acute inflammation, and, as a result, levels of this protein can be used to diagnose inflammatory conditions. Multiple AGP genes exist, including AGP-1, AGP-2, AGP-3 and AGP-8. AGP-1 and AGP-2 contain five and six potential N-glycosylation sites, respectively. Abnormal expression of the APG-1 gene is linked to sarcoidosis and other immunogenetic diseases, while mutations in the APG-2 gene are associated with different types of carcinomas.

Specifications

• Antigen: Orosomucoid 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ORM2
• Gene Alias: AGP 2; Agp1; AGP2; Agp-2; AGP-B; AGP-B′; alpha-1-acid glycoprotein 1; Alpha-1-acid glycoprotein 2; alpha-1-acid glycoprotein, type 2; bM340H1.5 (orosomucoid 2); OMD 2; OMD2; Orm2; Orm-2; orosomucoid 2; Orosomucoid2; Orosomucoid-2
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 5005
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: P19652
• Gene Symbols: ORM2
• Immunogen: KLH conjugated synthetic peptide derived from human Orosomucoid 2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG