Invitrogen™ ORP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589675

Catalog No. PIPA589675

Description

Immunogen sequence: NKKKLFMIYG KWTECLWGID PVSYESFKKQ ERRGDHLRKA KLDEDSGKAD SDVADDVPVA QETVQVIPGS KLLWRINTRP PNSAQMYNFT SFTVSLNELE TGMEKTLPPT DCRLRPDIRG MENGNMDLAS QEKERLEEKQ REARRERAKE EAEWQTRWFY PGNNPYTGTP DWLYAGDYFE RNFSDCPDIY; Positive Samples: U-251MG, A549, HepG2, HeLa.

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.

Specifications

• Antigen: ORP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OSBPL2
• Gene Alias: C130070J12Rik; DFNA67; DNFA67; FLJ20223; KIAA0772; MGC4307; MGC8342; mKIAA0772; ORP2; ORP-2; Osbpl2; OSBP-related protein 2; oxysterol binding protein like 2; oxysterol binding protein-like 2; oxysterol-binding protein-like 2; oxysterol-binding protein-related protein 2; RP11-157P1.2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9885
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.01 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q9H1P3
• Gene Symbols: OSBPL2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 291-480 of human OSBPL2 (NP_6530811).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov