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OSCAR Monoclonal Antibody (5B8), Invitrogen™

Catalog No. PIMA533374
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100 μg
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Catalog No. Quantity
PIMA533374 100 μg
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Catalog No. PIMA533374 Supplier Thermo Scientific Supplier No. MA533374

Description

Rat Monoclonal Antibody

Product is supplied at 1 mL (100 μL/mL).

Recently, a novel member of the leukocyte receptor complex (LRC) encoded family has been identified that is expressed specifically in osteoclast (OC). This protein names OC-associated receptor or OSCAR, play critical roles in the regulation of both innate and adaptive immune responses and bone-specific regulator of OC differentiation. Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This protein family plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OSCAR
Applications Flow Cytometry, Functional Assay
Classification Monoclonal
Clone 5B8
Concentration 100 μg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA and no preservative
Gene OSCAR
Gene Accession No. Q8VBT3
Gene Alias MGC33613; mOSCAR; mOSCAR-M1; mOSCAR-M2; mOSCAR-M3; ocl178; Oscar; osteoclast associated receptor; osteoclast associated receptor OSCAR-S1; osteoclast associated receptor OSCAR-S2; osteoclast associated, immunoglobulin-like receptor; osteoclast-associated immunoglobulin-like receptor; Osteoclast-associated receptor; osteoclast-associated receptor OSCAR; PIGR3; PIgR-3; poly-Ig receptor 3; polymeric immunoglobulin receptor 3
Gene Symbols OSCAR
Host Species Rat
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 232790
Target Species Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG2b
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