Invitrogen™ OSCAR Monoclonal Antibody (C2), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA543635

Catalog No. PIMA543635

Description

Recently, a novel member of the leukocyte receptor complex (LRC) encoded family has been identified that is expressed specifically in osteoclast (OC). This protein names OC-associated receptor or OSCAR, play critical roles in the regulation of both innate and adaptive immune responses and bone-specific regulator of OC differentiation. Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This protein family plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: OSCAR
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: Q8IYS5
• Gene Symbols: OSCAR
• Immunogen: Polypeptide conjugated human OVA. The polypeptide sequence is QGGIYRCCYRRPDWGP.
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Western Blot
• Clone: C2
• Conjugate: Unconjugated
• Gene: OSCAR
• Gene Alias: MGC33613; mOSCAR; mOSCAR-M1; mOSCAR-M2; mOSCAR-M3; ocl178; Oscar; osteoclast associated receptor; osteoclast associated receptor OSCAR-S1; osteoclast associated receptor OSCAR-S2; osteoclast associated, immunoglobulin-like receptor; osteoclast-associated immunoglobulin-like receptor; Osteoclast-associated receptor; osteoclast-associated receptor OSCAR; PIGR3; PIgR-3; poly-Ig receptor 3; polymeric immunoglobulin receptor 3
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 126014
• Content And Storage: -20°C
• Form: Liquid