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Invitrogen™ OSCAR Polyclonal Antibody
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Catalog No. PIPA5140332
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100 μL
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PIPA5140332 100 μL
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Catalog No. PIPA5140332 Supplier Invitrogen™ Supplier No. PA5140332
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: VGPGANVSLR CAGRLRNMSF VLYREGVAAP LQYRHSAQPW ADFTLLGARA PGTYSCYYH Highest antigen sequence indentity to the following orthologs: Rat - 68%, Mouse - 73%.

Recently, a novel member of the leukocyte receptor complex (LRC) encoded family has been identified that is expressed specifically in osteoclast (OC). This protein names OC-associated receptor or OSCAR, play critical roles in the regulation of both innate and adaptive immune responses and bone-specific regulator of OC differentiation. Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This protein family plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OSCAR
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene OSCAR
Gene Accession No. Q8IYS5
Gene Alias MGC33613; mOSCAR; mOSCAR-M1; mOSCAR-M2; mOSCAR-M3; ocl178; Oscar; osteoclast associated receptor; osteoclast associated receptor OSCAR-S1; osteoclast associated receptor OSCAR-S2; osteoclast associated, immunoglobulin-like receptor; osteoclast-associated immunoglobulin-like receptor; Osteoclast-associated receptor; osteoclast-associated receptor OSCAR; PIGR3; PIgR-3; poly-Ig receptor 3; polymeric immunoglobulin receptor 3
Gene Symbols OSCAR
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human OSCAR. Recombinant protein control fragment (Product #RP-109381).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 126014
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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