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Invitrogen™ OSMR Monoclonal Antibody (8F3H8B2)
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Catalog No. PIMA529458
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100 μL
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PIMA529458 100 μL
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Catalog No. PIMA529458 Supplier Invitrogen™ Supplier No. MA529458
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Description

Mouse Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human OSMR/IL31RB.

Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF.Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OSMR
Applications ELISA, Immunoprecipitation
Classification Monoclonal
Clone 8F3H8B2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene OSMR
Gene Accession No. Q99650
Gene Alias IL-31 receptor subunit beta; IL-31R subunit beta; IL-31RB; IL-31R-beta; interleukin-31 receptor subunit beta; MGC150626; MGC150627; MGC75127; oncostatin M receptor; oncostatin receptor; oncostatin-M specific receptor beta subunit; oncostatin-M specific receptor subunit beta; oncostatin-M-specific receptor subunit beta; OSMR; Osmrb; PLCA1
Gene Symbols OSMR
Host Species Mouse
Immunogen Recombinant Human OSMR protein (Met1-Met740).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9180
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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