OSSA Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Catalog No.	Quantity
50-156-6333	10 μL

Catalog No. 50-156-6333 Supplier Bethyl Laboratories, Inc Supplier No. A303889AT

Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

FAM120A (C9orf10) is a member of the constitutive coactivator of PPAR -gamma family and the gene was mapped to chromosome 9q22.31. FAM120A was recently detected within the Pur-alpha-containing mRNA-protein complex in the brain. As a novel RNA-binding protein, FAM120A is a critical component of the oxidative stress-induced survival signaling. It may participate in mRNA transport in the cytoplasm. FAM120A activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A protects cells from apoptosis through activation of SRKs in response to oxidative stress. Blocking of the survival signaling mediated by FAM120A, which sensitizes the cancer cells to stress-induced apoptosis, may be a novel therapeutic approach for gastric scirrhous carcinoma cells.

Specifications

• Antigen: OSSA
• Applications: Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/ml
• Conjugate: Unconjugated
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene: FAM120A
• Gene Accession No.: Q6A0A9, Q9NZB2
• Gene Alias: C9orf10, DNAPTP1, DNAPTP5, OSSA; DNA polymerase-transactivated protein 1; DNA polymerase-transactivated protein 5; constitutive coactivator of PPAR-gamma-like protein 1; oxidative stress-associated Src activator
• Gene Symbols: Fam120a
• Host Species: Rabbit
• Immunogen: Between 1068 and 1118
• Purification Method: Antigen affinity chromatography
• Quantity: 10 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 218236, 23196
• Target Species: Human, Mouse
• Content And Storage: 4° C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG