Osteoprotegerin (OPG) Mouse anti-Human, Clone: 98A1071, Active Motif™

Catalog No.	Quantity
50-199-3053	100 μg

Catalog No. 50-199-3053 Supplier Active Motif Supplier No. 40938

Description

Mouse Monoclonal Antibody

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Specifications

• Antigen: Osteoprotegerin (OPG)
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 98A1071
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.02% gelatin and 0.05% sodium azide; pH 7.5
• Gene: TNFRSF11B
• Gene Accession No.: O00300
• Gene Alias: MGC29565; Ocif; OPG; Osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; soluble OPG; soluble Osteoprotegerin; sOPG; TNF receptor superfamily member 11b; TNFRSF11B; TR1; Tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
• Gene Symbols: TNFRSF11B
• Host Species: Mouse
• Immunogen: This Osteoprotegerin (OPG) antibody was raised against a peptide corresponding to amino acid residues 20-37 of human Osteoprotegerin (OPG).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4982
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1