Osteoprotegerin (OPG) Mouse anti-Human, Clone: 98A1071, Active Motif™

Mouse Monoclonal Antibody

Supplier:  Active Motif 40938

Catalog No. 50-199-3053

Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Specifications

• Antigen: Osteoprotegerin (OPG)
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% gelatin and 0.05% sodium azide; pH 7.5
• Gene Accession No.: O00300
• Gene Symbols: TNFRSF11B
• Immunogen: This Osteoprotegerin (OPG) antibody was raised against a peptide corresponding to amino acid residues 20-37 of human Osteoprotegerin (OPG).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: 98A1071
• Conjugate: Unconjugated
• Gene: TNFRSF11B
• Gene Alias: MGC29565; Ocif; OPG; Osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; soluble OPG; soluble Osteoprotegerin; sOPG; TNF receptor superfamily member 11b; TNFRSF11B; TR1; Tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
• Host Species: Mouse
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4982
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid