Invitrogen™ OSTM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120130

Catalog No. PIPA5120130

Description

Positive test controls include: HeLa, 293T, A-549, Raji, B cells, Mouse brain, Mouse kidney. The target is usually found in the following locations: Lysosome membrane, Single-pass type I membrane protein. Immunogen sequence: ALPFGSSPHR VFHDLLSEQQ LLEVEDLSLS LLQGGGLGPL SLPPDLPDLD PECRELLLDF ANSSAELTGC LVRSARPVRL CQTCYPLFQQ VVSKMDNISR AAGNTSESQS CARSLLMADR MQIVVILSEF FNTTWQEANC ANCLTNNSEE LSNSTVYFLN LFNHTLTCFE HNLQGNAHSL LQTKNYSEVC KNCREAYKTL SSLYSEMQKM NELENKAEPG THLCIDVEDA MNITRKLWSR TFNCSVPCSD TVP.

This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.

Specifications

• Antigen: OSTM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OSTM1
• Gene Alias: 1200002H13Rik; Chloride channel 7 beta subunit; CLCN7 accessory beta subunit; GAIP interacting protein N terminus; GAIP-interacting protein N terminus; GIPN; GL; grey lethal osteopetrosis; grey-lethal osteopetrosis; Grey-lethal protein; HSPC019; OPTB5; osteopetrosis associated transmembrane protein 1; osteopetrosis associated transmembrane protein 1-like; osteopetrosis-associated transmembrane protein 1; Ostm1; UNQ6098/PRO21201
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14628, 28962
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 3.79 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q86WC4, Q8BGT0
• Gene Symbols: OSTM1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 32-284 of human OSTM1 (NP_054747.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG