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Invitrogen™ OTC Monoclonal Antibody (CL4046)
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Catalog No. PIMA531397
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100 μL
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PIMA531397 100 μL
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Catalog No. PIMA531397 Supplier Invitrogen™ Supplier No. MA531397
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Mouse Monoclonal Antibody

Immunogen sequence: ILADYLTLQE HYSSLKGLTL SWIGDGNNIL HSIMMSAAKF GMHLQAATPK GYEPDASVTK LAEQYAKENG TKLLLTNDPL EAAHGGNVLI TDTWISMGQE EEKKKRLQAF QGYQVTMKTA KVAASDWT Highest antigen sequence indentity to the following orthologs: Mouse - 93%, Rat - 92%.

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OTC
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone CL4046
Concentration 0.7 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene OTC
Gene Accession No. P00480
Gene Alias AI265390; OCTD; ornithine carbamoyltransferase; ornithine carbamoyltransferase, mitochondrial; Ornithine transcarbamylase; Otc; OTCase; Sf; sparse fur; spf
Gene Symbols OTC
Host Species Mouse
Immunogen Recombinant protein fragment of Human OTC (Product #RP-91882)
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5009
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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