Invitrogen™ OTC Monoclonal Antibody (CL4046)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531397

Catalog No. PIMA531397

Description

Immunogen sequence: ILADYLTLQE HYSSLKGLTL SWIGDGNNIL HSIMMSAAKF GMHLQAATPK GYEPDASVTK LAEQYAKENG TKLLLTNDPL EAAHGGNVLI TDTWISMGQE EEKKKRLQAF QGYQVTMKTA KVAASDWT Highest antigen sequence indentity to the following orthologs: Mouse - 93%, Rat - 92%.

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.

Specifications

• Antigen: OTC
• Classification: Monoclonal
• Concentration: 0.7 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P00480
• Gene Symbols: OTC
• Immunogen: Recombinant protein fragment of Human OTC (Product #RP-91882)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: CL4046
• Conjugate: Unconjugated
• Gene: OTC
• Gene Alias: AI265390; OCTD; ornithine carbamoyltransferase; ornithine carbamoyltransferase, mitochondrial; Ornithine transcarbamylase; Otc; OTCase; Sf; sparse fur; spf
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 5009
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid