Invitrogen™ OTC Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597260

Catalog No. PIPA597260

Description

Immunogen sequence: LQAATPKGYE PDASVTKLAE QYAKENGTKL LLTNDPLEAA HGGNVLITDT WISMGQEEEK KKRLQAFQGY QVTMKTAKVA ASDWTFLHCL PRKPEEVDDE VFYSPRSLVF PEAENRKWTI MAVMVSLLTD YSPQLQKPKF; Positive Samples: Mouse liver, Mouse small intestine, Rat liver, Rat small intestine; Cellular Location: Mitochondrion matrix.

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.

Specifications

• Antigen: OTC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OTC
• Gene Alias: AI265390; OCTD; ornithine carbamoyltransferase; ornithine carbamoyltransferase, mitochondrial; Ornithine transcarbamylase; Otc; OTCase; Sf; sparse fur; spf
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18416, 25611, 5009
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.72 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P00480, P00481, P11725
• Gene Symbols: OTC
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 215-354 of human OTC (NP_0005223).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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