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Invitrogen™ OTC Polyclonal Antibody
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Catalog No. PIPA597260
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100 μL
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PIPA597260 100 μL
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Catalog No. PIPA597260 Supplier Invitrogen™ Supplier No. PA597260
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LQAATPKGYE PDASVTKLAE QYAKENGTKL LLTNDPLEAA HGGNVLITDT WISMGQEEEK KKRLQAFQGY QVTMKTAKVA ASDWTFLHCL PRKPEEVDDE VFYSPRSLVF PEAENRKWTI MAVMVSLLTD YSPQLQKPKF; Positive Samples: Mouse liver, Mouse small intestine, Rat liver, Rat small intestine; Cellular Location: Mitochondrion matrix.

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OTC
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.72 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene OTC
Gene Accession No. P00480, P00481, P11725
Gene Alias AI265390; OCTD; ornithine carbamoyltransferase; ornithine carbamoyltransferase, mitochondrial; Ornithine transcarbamylase; Otc; OTCase; Sf; sparse fur; spf
Gene Symbols OTC
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 215-354 of human OTC (NP_0005223).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18416, 25611, 5009
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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