Invitrogen™ OTX2 Monoclonal Antibody (1H12G8B2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515855

Catalog No. PIMA515855

Description

MA5-15855 targets OTX2 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human samples. The MA5-15855 immunogen is purified recombinant fragment of human OTX2 expressed in E. Coli. . MA5-15855 detects OTX2 which has a predicted molecular weight of approximately 32kDa.

OTX2 is a 289 amino acid containing protein encoding a member of the bicoid sub-family of homeodomain-containing transcription factors. It has two known alternative splice variants with distinct isoforms though presence of other isoforms cannot be excluded. The protein is an early marker of endodermal differentiation of embryonic stem cells and may play a role in the development of the brain and the sensory organs. The proteinmay bind to BCD target sequence (BTS): 5-'TCTAATCCC-3'. Defects in OTX2 are the cause of microphthalmia syndromic type 5 (MCOPS5).

Specifications

• Antigen: OTX2
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Ascites with 0.03% sodium azide
• Gene Accession No.: P32243, P80206, Q64201
• Gene Symbols: OTX2
• Immunogen: Purified recombinant fragment of human OTX2 expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 18424, 305858, 5015
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 1H12G8B2
• Conjugate: Unconjugated
• Gene: OTX2
• Gene Alias: CPHD6; E130306E05Rik; homeobox Otx2; homeobox protein OTX2; MCOPS5; orthodenticle homeobox 2; orthodenticle homolog 2; OTX; OTX2
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1