OTX2 Mouse anti-Human, Clone: OTI1A1, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF809511

Catalog No. 50-166-9547

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

OTX2 is a 289 amino acid containing protein encoding a member of the bicoid sub-family of homeodomain-containing transcription factors. It has two known alternative splice variants with distinct isoforms though presence of other isoforms cannot be excluded. The protein is an early marker of endodermal differentiation of embryonic stem cells and may play a role in the development of the brain and the sensory organs. The proteinmay bind to BCD target sequence (BTS): 5-′TCTAATCCC-3′. Defects in OTX2 are the cause of microphthalmia syndromic type 5 (MCOPS5).

Specifications

• Antigen: OTX2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: OTX2
• Gene Alias: CPHD6, MCOPS5
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5015
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1A1
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P32243
• Gene Symbols: OTX2
• Immunogen: Full length human recombit protein of human OTX2 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1