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Invitrogen™ OTX2 Recombinant Rabbit Monoclonal Antibody (14H14L5)

Catalog No. 701948
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Catalog No. Quantity
70-194-8 100 μg
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Catalog No. 70-194-8 Supplier Invitrogen™ Supplier No. 701948
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Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Rat, Mouse, Pig and Sheep. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

OTX2 is a 289 amino acid containing protein encoding a member of the bicoid sub-family of homeodomain-containing transcription factors. It has two known alternative splice variants with distinct isoforms though presence of other isoforms cannot be excluded. The protein is an early marker of endodermal differentiation of embryonic stem cells and may play a role in the development of the brain and the sensory organs. The proteinmay bind to BCD target sequence (BTS): 5-'TCTAATCCC-3'. Defects in OTX2 are the cause of microphthalmia syndromic type 5 (MCOPS5).
TRUSTED_SUSTAINABILITY

Specifications

Antigen OTX2
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 14H14L5
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene OTX2
Gene Accession No. P32243, P80206, Q64201
Gene Alias CPHD6; E130306E05Rik; homeobox Otx2; homeobox protein OTX2; MCOPS5; orthodenticle homeobox 2; orthodenticle homolog 2; OTX; OTX2
Gene Symbols OTX2
Host Species Rabbit
Immunogen Peptides corresponding to Human OTX2 (aa 20-39, 276-289).
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18424, 305858, 5015
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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