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Invitrogen™ OVCA2 Polyclonal Antibody
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Catalog No. PIPA531447
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100 μL
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PIPA531447 100 μL
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Catalog No. PIPA531447 Supplier Invitrogen™ Supplier No. PA531447
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, Raji. Predicted reactivity: Mouse (83%), Rat (84%), Bovine (83%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Chromosome 17 is a hotspot for chromosomal aberrations in breast and ovarian cancer. Candidate oncogenes and tumor suppressors located on this chromosome include OVCA1 and OVCA2, p53, BRCA1, HER2/neu and others. OVCA1 and 2 map to a highly conserved region on human chromosome 17p13.3 that is deleted in 80% of ovarian cancers and shows frequent loss of heterozygosity in breast cancers. OVCA1 is induced by BRCA1 and is closely linked to p53, a well-known tumor suppressor gene. The close linkage of OVCA1 and p53 suggests that coordinated loss of the two genes may lead to ovarian, breast and other tumor types.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OVCA2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene OVCA2
Gene Accession No. Q8WZ82
Gene Alias 9030414M07Rik; candidate tumor suppressor in ovarian cancer 2; candidate tumor suppressor OVCA2; esterase OVCA2; hypothetical protein LOC534099; ortholog of human candidate tumor suppressor in ovarian cancer 2 OVCA2; ovarian cancer gene-2 protein; ovarian cancer-associated gene 2 protein; Ovarian cancer-associated gene 2 protein homolog; ovarian tumor suppressor candidate 2; Ovca2; OVCA2 serine hydrolase domain containing; OVCA2, serine hydrolase domain containing; RGD1564623
Gene Symbols OVCA2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human OVCA2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 124641
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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