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Invitrogen™ Ovine IL-17A ELISA Kit Non-distribution product as customer accommodation.

Ovine IL-17A quantitates ovine IL-17A in serum, plasma, supernatant.

$491.00 - $2205.00

Specifications

Regulatory Status Research Use Only
Storage Requirements 2°C to 8°C
Target IL-17 A
Product Type ELISA
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
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Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
ESH3RBX5 Non-distribution product as customer accommodation.
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Invitrogen™
ESH3RBX5
5 x 96 Tests
Each for $2,205.00
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ESH3RB Non-distribution product as customer accommodation.
View Documents
Invitrogen™
ESH3RB
96 Tests
Each for $491.00
Add to cart
 
Description

Description

Ovine IL-17A quantitates ovine IL-17A in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant ovine IL-17A.

Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection. IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217). High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts. In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to secrete IL-6, IL-8, G-CSF, and PGE2. In the presence of human IL-17A, fibroblasts can sustain the proliferation of CD34+ hematopoietic progenitors and induce maturation into neutrophils. Mouse, rat, and human IL-17A can induce IL-6 secretion in mouse stromal cells, indicating that all homologs can recognize the mouse receptor. IL-17A regulates the activities of NF-kappa B and mitogen-activated protein kinases, stimulates the expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), and enhances the production of nitric oxide (NO).
Specifications

Specifications

Research Use Only
IL-17 A
Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
4 hr 45 min
Serum, Plasma, Supernatant
2°C to 8°C
ELISA
0.45 pg/mL
1 hr 20 min
Plasma, 50 µL; Supernatant, 50 µL; Serum, 50 µL
SDS
Product Certifications
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