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Tocris Bioscience™ OX 04528
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Quantity:
10 mg
50 mg
Description
OX 04528 is a highly potent and selective GPR84 agonist. It inhibits cAMP production in CHO cells expressing human GPR84 (EC50 = 6 pM) and shows no β-arrestin recruitment. Exhibits selectivity for GPR84 over FFA1, FFA4, and CB2 receptors. In vivo, OX 04528 shows a half-life of 58 minutes following oral dosing at 10 mg/kg in mouse pharmacokinetic studies. OX 04528 is orally bioavailable.
Specifications
Specifications
Chemical Name or Material | 3-(3-(3,5-Bis(trifluoromethyl)phenyl)propyl)-5-hydroxypyridine-1-oxide |
CAS | 3028055-45-7 |
Quantity | 50 mg |
Target | Orphan 7-TM Receptor Agonists |
Molecular Formula | C16H13F6NO2 |
Purity | 0.98 |
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