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Tocris Bioscience™ OX 04528

Catalog No. 813150
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Highly potent and selective GPR84 agonist

OX 04528 is a highly potent and selective GPR84 agonist. It inhibits cAMP production in CHO cells expressing human GPR84 (EC50 = 6 pM) and shows no β-arrestin recruitment. Exhibits selectivity for GPR84 over FFA1, FFA4, and CB2 receptors. In vivo, OX 04528 shows a half-life of 58 minutes following oral dosing at 10 mg/kg in mouse pharmacokinetic studies. OX 04528 is orally bioavailable.

Specifications

Chemical Name or Material 3-(3-(3,5-Bis(trifluoromethyl)phenyl)propyl)-5-hydroxypyridine-1-oxide
CAS 3028055-45-7
Quantity 50 mg
Target Orphan 7-TM Receptor Agonists
Molecular Formula C16H13F6NO2
Purity 0.98
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