OX40/TNFRSF4 Antibody (7D6), DyLight 650

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NB10064375C

Catalog No. NB10064375C

Description

OX40/TNFRSF4 Monoclonal specifically detects OX40/TNFRSF4 in Feline samples. It is validated for Western Blot, Flow Cytometry.

Specifications

• Antigen: OX40/TNFRSF4
• Classification: Monoclonal
• Conjugate: DyLight 650
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Symbols: TNFRSF4
• Immunogen: CHO-derived feline CD134-Fc fusion protein.
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: NB100-64375 recognizes feline CD134, otherwise known as OX40, a 43kDa type I membrane protein and member of the tumor necrosis factor receptor superfamily, expressed predominantly by CD4+ activated T cells, and a key regulator of T cell-dependent immune responses. CD134 has been identified as the receptor for the OX40 ligand, CD252, expressed by activated B cells, acting as a co-stimulatory signal for the stimulation and secretion of immunoglobulins. CD134 has also been identified as a binding receptor for Feline Immunodeficiency Virus (FIV), acting along with CXC chemokine receptor 4 (CXCR4) to facilitate the entry of the virus into CD4+ primary target cells.
• Content And Storage: Store at 4°C in the dark.

• Applications: Western Blot, Flow Cytometry
• Clone: 7D6
• Dilution: Western Blot, Flow Cytometry
• Gene Alias: ACT35 antigen, ACT35ATC35 antigen, CD134, CD134 antigen, OX40 cell surface antigen, OX40 homologue, OX40L receptor, OX40lymphoid activation antigene ACT35, TAX transcriptionally-activated glycoprotein 1 receptor, tax-transcriptionally activated glycoprotein 1 receptor, tumor necrosis factor receptor superfamily member 4, tumor necrosis factor receptor superfamily, member 4, TXGP1LOX40 antigen
• Host Species: Mouse
• Purification Method: Protein A purified
• Research Discipline: Adaptive Immunity, B Cell Development and Differentiation Markers, Cancer, Cell Cycle and Replication, Immunology, Myeloid derived Suppressor Cell, Signal Transduction
• Gene ID (Entrez): 7293.0
• Target Species: Feline
• Isotype: IgG1