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Invitrogen™ OX40L Monoclonal Antibody (OX89), Biotin
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Catalog No. PIMA517911
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100 μg
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PIMA517911 100 μg
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Catalog No. PIMA517911 Supplier Invitrogen™ Supplier No. MA517911
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Description

Rat Monoclonal Antibody

MA5-17911 targets CD134L/OX40L in FACS and IHC applications and shows reactivity with Mouse samples. The MA5-17911 immunogen is cD4.CD134L chimeric protein.

The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNgamma. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OX40L
Applications Flow Cytometry, Immunohistochemistry
Classification Monoclonal
Clone OX89
Concentration 0.1 mg/mL
Conjugate Biotin
Formulation PBS with 4-5mg/mL BSA and 0.02% sodium azide
Gene Tnfsf4
Gene Accession No. P43488
Gene Alias Ath1; Ath-1; atherosclerosis 1; CD134 ligand; CD134L; CD252; glycoprotein Gp34; GP34; OX40 antigen ligand; OX40 ligand; OX40L; OX-40L; OX4OL; TAX transcriptionally-activated glycoprotein 1; tax-transcriptionally activated glycoprotein 1 (34kD); tax-transcriptionally activated glycoprotein 1 ligand; TNFSF4; TNLG2B; tumor necrosis factor (ligand) superfamily member 4; tumor necrosis factor (ligand) superfamily, member 4; tumor necrosis factor ligand 2B; tumor necrosis factor ligand superfamily member 4; tumor necrosis factor superfamily member 4; TXGP1; Txgp1l
Gene Symbols Tnfsf4
Host Species Rat
Immunogen CD4.CD134L chimeric protein.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22164
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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