Invitrogen™ OXER1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102296

Catalog No. PIPA5102296

Description

Antibody detects endogenous levels of total OXER1.

TG1019 is a G protein-coupled receptor that functions as a chemoattractant for eosinophils and neutrophils. TG1019 is expressed in various tissues except the brain, with the highest expression in liver, kidney, peripheral leukocyte, lung and spleen. TG1019 interacts with the protein OXE to form TG1019/OXE, a Galpha i/o protein-coupled receptor. Signals from TG1019 are transduced via a Galpha i/o protein to PLC/calcium, MEK/ERK and PI3K/Akt pathways. Signal transduction from TG1019 following stimulation with 5-oxo-6E,8Z,11Z,14Z eicosatetraenoic acid (5-oxo-ETE) induces intracellular calcium mobilization and rapid activation of MEK/ERK and PI3K/Akt pathways. TG1019 also may play a role in downregulating cAMP production.

Specifications

• Antigen: OXER1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OXER1
• Gene Alias: 5-oxo-ETE acid G-protein-coupled receptor 1; 5-oxo-ETE G-protein coupled receptor; GPCR; GPR170; G-protein coupled receptor 170; G-protein coupled receptor R527; G-protein coupled receptor TG1019; HEOAD54; OXE receptor; OXER1; oxoeicosanoid (OXE) receptor 1; oxoeicosanoid receptor 1; TG1019
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 165140
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8TDS5
• Gene Symbols: OXER1
• Immunogen: A synthesized peptide derived from human OXER1(Accession Q8TDS5), corresponding to amino acid residues I220-F270.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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