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OXER1 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA132732
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25 μg
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Catalog No. Quantity
PIPA132732 25 μg
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Catalog No. PIPA132732 Supplier Thermo Scientific Supplier No. PA132732

Description

Rabbit Polyclonal Antibody

PA1-32732 detects GPCR TG1019 from human samples.

TG1019 is a G protein-coupled receptor that functions as a chemoattractant for eosinophils and neutrophils. TG1019 is expressed in various tissues except the brain, with the highest expression in liver, kidney, peripheral leukocyte, lung and spleen. TG1019 interacts with the protein OXE to form TG1019/OXE, a Galpha i/o protein-coupled receptor. Signals from TG1019 are transduced via a Galpha i/o protein to PLC/calcium, MEK/ERK and PI3K/Akt pathways. Signal transduction from TG1019 following stimulation with 5-oxo-6E,8Z,11Z,14Z eicosatetraenoic acid (5-oxo-ETE) induces intracellular calcium mobilization and rapid activation of MEK/ERK and PI3K/Akt pathways. TG1019 also may play a role in downregulating cAMP production.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OXER1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene OXER1
Gene Accession No. Q8TDS5
Gene Alias 5-oxo-ETE acid G-protein-coupled receptor 1; 5-oxo-ETE G-protein coupled receptor; GPCR; GPR170; G-protein coupled receptor 170; G-protein coupled receptor R527; G-protein coupled receptor TG1019; HEOAD54; OXE receptor; OXER1; oxoeicosanoid (OXE) receptor 1; oxoeicosanoid receptor 1; TG1019
Gene Symbols OXER1
Host Species Rabbit
Immunogen Synthetic 19 amino acid peptide from C-terminus of human TG1019
Purification Method Antigen affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 165140
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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