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Invitrogen™ Oxytocin Receptor Polyclonal Antibody
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Catalog No. PIPA532961
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50 μg
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Catalog No. Quantity
PIPA532961 50 μg
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Catalog No. PIPA532961 Supplier Invitrogen™ Supplier No. PA532961
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey (95%); Marmoset (89%); Mouse, Dog (84%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

The oxytocin receptor (OXTR) belongs to the G-protein coupled receptor family. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The receptor is made up of 389 amino acids and has a molecular weight of ~43,000 kDa. The oxytocin-oxytocin receptor system plays an important role as an inducer of uterine contractions during parturition and of milk ejection. Oxytocin receptors are expressed by the myoepithelial cells of the mammary gland, and in both the myometrium and endometrium or the uterus at the end of pregnancy. Additionally, oxytocin receptors are present in the central nervous system, mediating a variety of behaviors, including maternal behavior, bonding, social memory and recognition, sexual and aggressive behaviors, and stress and anxiety.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Oxytocin Receptor
Applications ELISA, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene Oxtr
Gene Accession No. P30559
Gene Alias Otr; OT-R; OTR1; oxcytocin receptor; OXTR; Oxt-r; Oxytocin receptor
Gene Symbols Oxtr
Host Species Rabbit
Immunogen Synthetic 19 amino acid peptide from C-terminal cytoplasmic domain of human Oxytocin Receptor.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5021
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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