Invitrogen™ Oxytocin Receptor Recombinant Rabbit Monoclonal Antibody (7X8B8)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA537974

Catalog No. PIMA537974

Description

Positive Samples: HeLa, PC-3, Jukat, Mouse brain Immunogen sequence: LLLALSGNAC VLLALRTTRQ KHSRLFFFMK HLSIADLVVA VFQVLPQLLW DITFRFYGPD LLCRLVKYLQ VVGMFASTYL LLLMSLDRCL AICQPLRSLR R.

The oxytocin receptor (OXTR) belongs to the G-protein coupled receptor family. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The receptor is made up of 389 amino acids and has a molecular weight of ~43,000 kDa. The oxytocin-oxytocin receptor system plays an important role as an inducer of uterine contractions during parturition and of milk ejection. Oxytocin receptors are expressed by the myoepithelial cells of the mammary gland, and in both the myometrium and endometrium or the uterus at the end of pregnancy. Additionally, oxytocin receptors are present in the central nervous system, mediating a variety of behaviors, including maternal behavior, bonding, social memory and recognition, sexual and aggressive behaviors, and stress and anxiety.

Specifications

• Antigen: Oxytocin Receptor
• Classification: Recombinant Monoclonal
• Concentration: 1.2 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P30559, P70536, P97926
• Gene Symbols: Oxtr
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Oxytocin Receptor (P30559).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 7X8B8
• Conjugate: Unconjugated
• Gene: Oxtr
• Gene Alias: Otr; OT-R; OTR1; oxcytocin receptor; OXTR; Oxt-r; Oxytocin receptor
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18430, 25342, 5021
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov