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P-cadherin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 137731AP150UL

Description
P-cadherin, also known as Cadherin-3, is a Type 1 cadherin protein that belongs to the cadherin superfamily. Type 1 cadherins are single-pass transmembrane proteins that have 5 extracellular cadherin repeats and an intracellular domain that binds p120-catenin and beta-catenin. Cadherins are calcium-dependent cell-cell adhesion glycoproteins responsible for a range of processes including development, wound healing, cell-cell signaling, cell growth and differentiation. P-cadherin is expressed in human fetal structures, and in adult tissues such as the basal layer of the epidermis, breast, prostate, ovary, cervix, hair follicle, and corneal endothelium. P-cadherin expression has also been reported on embryonic stem cells, and stem cells of the normal mammary gland, and hair follicle. Overexpression of P-cadherin has been associated with poor prognosis in breast, prostate, ovary, colon, and stomach carcinomas. Mutations in CDH3 are associated with congential hypotrichosis with juvenile macular dystrophy.Specifications
P-cadherin | |
Polyclonal | |
Unconjugated | |
CDH3 | |
Cadherin 3, CDH3, CDHP, HJMD, PCAD, P-cadherin | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
1001, 116777, 12560 | |
-20°C | |
Liquid |
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation | |
0.3 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P10287, P22223 | |
CDH3 | |
P-cadherin Fusion Protein Ag4758 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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