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p130Cas Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501731196 Shop All Proteintech Group Inc Products
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50-173-1196 150 μL
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Catalog No. 50-173-1196 Supplier Proteintech Group Inc Supplier No. 168151AP150UL
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Description

Rabbit Polyclonal Antibody

The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.

Specifications

Antigen p130Cas
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.27 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene BCAR1
Gene Accession No. P56945, Q61140, Q63767
Gene Alias BCAR1, CAS, CAS1, CASS1, CRK associated substrate, CRKAS, p130Cas
Gene Symbols BCAR1
Host Species Rabbit
Immunogen p130Cas Fusion Protein Ag10354
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12927, 25414, 9564
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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