p21WAF1 Ab-6 Mouse Monoclonal Antibody, Epredia™

Achieve accurate, reproducible results with the Epredia™ p21^WAF1 Ab-6, Mouse Monoclonal Antibody.

Supplier:  Epredia MS454P1ABX

Catalog No. MS454P1ABX

Description

p21^WAF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21^WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21^WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process.

Host Species: Mouse

Clone: HJ21; same as WA-1

Isotype: IgG1

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Human recombinant p21 protein

Molecular Weight: 21kDa

Positive Control: PC12, Ls174T or Raji cells

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Not suitable)
• Western Blotting
• Immunofluorescence
• Immunoprecipitation (Not suitable)
• Flow Cytometry (Not Suitable)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: p21WAF1 Ab-6
• Classification: Monoclonal
• Concentration: 1mg/mL
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: Cancer and Tumor Biology
• Target Species: Human, Rat
• Isotype: IgG1

• Applications: Immunofluorescence, Western Blot
• Clone: HJ21; same as WA-1
• Conjugate: Unconjugated
• Immunogen: Human recombinant p21 protein
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated