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  6. p21WAF1Ab-3 Mouse Monoclonal Antibody, Epredia™

p21WAF1Ab-3 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS230P0 Shop All Epredia Products
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Quantity:
100 μL
200 μL
1 mL
7 mL
Form:
Concentrated
Prediluted
Concentration:
—
1mg/mL
200μg/mL
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Catalog No. Quantity Form Concentration
MS230P0 100 μL Concentrated 200μg/mL
MS230P 1 mL Concentrated 200μg/mL
MS230P1ABX 100 μL Concentrated 1mg/mL
MS230PABX 200 μL Concentrated 1mg/mL
MS230R1 1 mL Prediluted —
MS230R7 7 mL Prediluted —
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Catalog No. MS230P0 Supplier Epredia Supplier No. MS230P0

Description

Achieve accurate, reproducible results with the Epredia™ p21WAF1 Ab-3, Mouse Monoclonal Antibody.

p21WAF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process.

Host Species: Mouse

Clone: DCS-60.2

Isotype: IgG2a

Species Reactivity: Human. Does not react with mouse and rat. Others not known

Epitope: Not determined

Immunogen: Full-length human recombinant p21 protein

Molecular Weight: 21kDa

Positive Control: Ls174T or Raji cells, Colon CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not suitable)
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Flow Cytometry (Not suitable)

Specifications

Antigen p21WAF1 Ab-3
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Monoclonal
Clone DCS-60.2
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Full length human recombinant p21 protein
Quantity 100 μL
Regulatory Status IVD
Research Discipline Cancer and Tumor Biology
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG2a
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