Invitrogen™ P2X1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5144864

Catalog No. FEPA5144864

Description

Immunogen sequence: LFIKNSISFP RFKVNRRNLV EEVNAAHMKT CLFHKTLHPL CPVFQLGYVV QESGQNFSTL AEKGGVV Antigen sequence identity: Mouse 84%; Rat 82%.

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.

Specifications

• Antigen: P2X1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: P2RX1
• Gene Alias: AI323649; ATP receptor; BB122383; P2RX1; P2x; P2X purinoceptor 1; P2X receptor, subunit 1; P2X1; P2X1 receptor; P2XMR; Pdcd3; programmed cell death 3; Purinergic receptor; purinergic receptor P2X 1; purinergic receptor P2X, ligand gated ion channel, 1; purinergic receptor P2X, ligand-gated ion channel, 1; purinergic receptor P2X1; purinergic receptor P2X1-1; purinergic receptor P2X1-2; RP-2; RP-2 protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5023
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid
• Isotype: IgG

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P51575
• Gene Symbols: P2RX1
• Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 187-253. Recombinant protein control fragment (Product #RP-110019).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Format: Liquid