P2X5 (extracellular) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA577683

Catalog No. PIPA577683

Description

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 μL of deionized water.

Mmgt2 mediates Mg(2+) transport and may provide regulated pathways for Mg(2+) transport in the Golgi and post-Golgi organelles of epithelium-derived cells. Magnesium is an essential metal, but few selective transporters have been identified. The two separate gene products, Mmgt1 and Mmgt2, comprise the family that we have termed membrane Mg(2+) transporters (MMgTs), and the proteins reside in the membrane and mediate Mg(2+) transport. The transport of Mg(2+) is saturable and studies have identified that Mmgt2 fusion proteins reside in the Golgi complex and post-Golgi vesicles, including the early endosomes in COS-7 cells transfected with the respective tagged constructs. Among related pathways for Mmgt2 are transport and binding events, in particular, transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds.

Specifications

• Antigen: P2X5 (extracellular)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mmgt2
• Gene Alias: P2X5 Receptor (extracellular)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 216829, 303211
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 0.85 mg/mL
• Formulation: PBS with 1% BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q6P719, Q8R3L0
• Gene Symbols: Mmgt2
• Immunogen: Peptide (C)HRSHTRLAEMKYE, corresponding to amino acid residues 299-311 of rat P2X5 receptor
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG