P2X5 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA528838

Catalog No. PIPA528838

Description

Recommended positive controls: A431, HeLa, HepG2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Mmgt2 mediates Mg(2+) transport and may provide regulated pathways for Mg(2+) transport in the Golgi and post-Golgi organelles of epithelium-derived cells. Magnesium is an essential metal, but few selective transporters have been identified. The two separate gene products, Mmgt1 and Mmgt2, comprise the family that we have termed membrane Mg(2+) transporters (MMgTs), and the proteins reside in the membrane and mediate Mg(2+) transport. The transport of Mg(2+) is saturable and studies have identified that Mmgt2 fusion proteins reside in the Golgi complex and post-Golgi vesicles, including the early endosomes in COS-7 cells transfected with the respective tagged constructs. Among related pathways for Mmgt2 are transport and binding events, in particular, transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds.

Specifications

• Antigen: P2X5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: P2RX5
• Gene Alias: AI852046; ATP receptor; ATP receptor subunit; ionotropic ATP receptor P2X5; LRH-1; lymphoid-restricted histocompatibility antigen-1; membrane magnesium transporter 2; membrane magnesium transporter 2 {ECO:0000250; MGC47755; Mmgt2; mmgt2 {ECO:0000250; P2 purinergic receptor subtype; P2RX5; P2X purinoceptor 5; P2X5; P2X5 purinoceptor; P2x5 receptor; P2X5R; Purinergic receptor; purinergic receptor P2X 5; purinergic receptor P2X, ligand gated ion channel, 5; purinergic receptor P2X, ligand-gated ion channel, 5; purinergic receptor P2X5-1; purinergic receptor P2X5-2; RGD1311260; UniProtKB:Q8R3L0}
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5026
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.15 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q93086
• Gene Symbols: P2RX5
• Immunogen: Synthetic peptide corresponding to a region within amino acids 358 and 422 of Human P2X5
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov