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Invitrogen™ P2X7 Monoclonal Antibody (Hano43)
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Catalog No. PIMA528184
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250 μg
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Catalog No. Quantity
PIMA528184 250 μg
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Catalog No. PIMA528184 Supplier Invitrogen™ Supplier No. MA528184
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Description

Rat Monoclonal Antibody

Rat anti Mouse P2X7 antibody, clone Hano43 recognizes the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic.

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay criteria.
TRUSTED_SUSTAINABILITY

Specifications

Antigen P2X7
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone Hano43
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Gene P2RX7
Gene Accession No. Q9Z1M0
Gene Alias AI467586; ATP receptor; MGC20089; P2rx7; P2X purinoceptor 7; p2X receptor 7; P2X(7); P2X7; P2X7 purinoceptor; P2X7 receptor; P2X7R; P2Z; P2Z receptor; Purinergic receptor; purinergic receptor P2X 7; purinergic receptor P2X, ligand gated ion channel, 7; purinergic receptor P2X, ligand-gated ion channel, 7; purinergic receptor P2X7; purinergic receptor P2X7 variant A
Gene Symbols P2RX7
Host Species Rat
Immunogen A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Purification Method Protein G
Quantity 250 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18439
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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