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Invitrogen™ P2X7 Polyclonal Antibody
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Catalog No. PIPA5111049
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100 μL
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PIPA5111049 100 μL
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Catalog No. PIPA5111049 Supplier Invitrogen™ Supplier No. PA5111049
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Rabbit Polyclonal Antibody

Immunogen sequence: CRSHIYPWCK CCQPCVVNEY YYRKKCESIV EPKPTLKYVS FVDESHIRMV NQQLLGRSLQ DVKGQEVPRP AMDFTDLSR Highest antigen sequence indentity to the following orthologs: Mouse - 85%, Rat - 82%.

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay criteria.
TRUSTED_SUSTAINABILITY

Specifications

Antigen P2X7
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.9 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene P2RX7
Gene Accession No. Q99572
Gene Alias AI467586; ATP receptor; MGC20089; P2rx7; P2X purinoceptor 7; p2X receptor 7; P2X(7); P2X7; P2X7 purinoceptor; P2X7 receptor; P2X7R; P2Z; P2Z receptor; Purinergic receptor; purinergic receptor P2X 7; purinergic receptor P2X, ligand gated ion channel, 7; purinergic receptor P2X, ligand-gated ion channel, 7; purinergic receptor P2X7; purinergic receptor P2X7 variant A
Gene Symbols P2RX7
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human P2X7. Recombinant protein control fragment (Product #RP-94974).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5027
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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