Invitrogen™ P2X7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIPA5111049	Invitrogen™ PA5111049	100 μL

Description

Immunogen sequence: CRSHIYPWCK CCQPCVVNEY YYRKKCESIV EPKPTLKYVS FVDESHIRMV NQQLLGRSLQ DVKGQEVPRP AMDFTDLSR.

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay criteria.

Specifications

• Antigen: P2X7
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q99572
• Gene ID (Entrez): 5027
• Immunogen: Recombinant Protein corresonding to Human P2X7. Recombinant protein control fragment (Product #RP-94974).
• Product Type: Antibody

• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: P2RX7
• Gene Alias: AI467586; ATP receptor; MGC20089; P2rx7; P2X purinoceptor 7; p2X receptor 7; P2X(7); P2X7; P2X7 purinoceptor; P2X7 receptor; P2X7R; P2Z; P2Z receptor; Purinergic receptor; purinergic receptor P2X 7; purinergic receptor P2X, ligand gated ion channel, 7; purinergic receptor P2X, ligand-gated ion channel, 7; purinergic receptor P2X7; purinergic receptor P2X7 variant A
• Gene Symbols: P2RX7
• Primary or Secondary: Primary
• Purification Method: Antigen affinity chromatography