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Invitrogen™ P2X7 Polyclonal Antibody
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Catalog No. PIPA587959
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100 μL
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PIPA587959 100 μL
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Catalog No. PIPA587959 Supplier Invitrogen™ Supplier No. PA587959
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Description

Rabbit Polyclonal Antibody

Positive Samples: A375, HT-29, U-251MG, LO2, Mouse heart, Rat liver; Cellular Location: Cell membrane, Multi-pass membrane protein Immunogen sequence: SDKLYQRKEP VISSVHTKVK GIAEVKEEIV ENGVKKLVHS VFDTADYTFP LQGNSFFVMT NFLKTEGQEQ RLCPEYPTRR TLCSSDRGCK KGWMDPQSKG IQTGRCVVYE GNQKTCEVSA WCPIEAVEEA PRPALLNSAE NFTVLIKNNI DFPGHNYTTR NILPGLNITC TFHKTQNPQC PIFRLGDIFR ETGDNFSDVA IQGGIMGIEI YWDCNLDRWF HHCRPKYSFR RLDDKTTNVS LYPGYNFRYA KYYKENNVEK RTLIKVFGIR FDILVFGTGG KFDIIQLV.

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay criteria.
TRUSTED_SUSTAINABILITY

Specifications

Antigen P2X7
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.21 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene P2RX7
Gene Accession No. Q64663, Q99572, Q9Z1M0
Gene Alias AI467586; ATP receptor; MGC20089; P2rx7; P2X purinoceptor 7; p2X receptor 7; P2X(7); P2X7; P2X7 purinoceptor; P2X7 receptor; P2X7R; P2Z; P2Z receptor; Purinergic receptor; purinergic receptor P2X 7; purinergic receptor P2X, ligand gated ion channel, 7; purinergic receptor P2X, ligand-gated ion channel, 7; purinergic receptor P2X7; purinergic receptor P2X7 variant A
Gene Symbols P2RX7
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 47-334 of human P2RX7 (NP_0025533).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18439, 29665, 5027
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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