Invitrogen™ P2Y12 Monoclonal Antibody (1C2A9)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531816

Catalog No. PIMA531816

Description

Amino acid sequence of the immunogen is proprietary. This antibody has been tested in indirect ELISA.

P2Y12 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene. Expression of P2Y12 has been reported in platelets, spinal cord, and many brain regions. ESTs for P2Y12 have been isolated from B-cell/lung/testis, brain, embryo, prostate, eye, kidney carcinoma, and colon carcinoma libraries.

Specifications

• Antigen: P2Y12
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q9H244
• Gene Symbols: P2ry12
• Immunogen: Purified recombinant fragment of human P2RY12 expressed in E. coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: 1C2A9
• Conjugate: Unconjugated
• Gene: P2ry12
• Gene Alias: 2900079B22Rik; 4921504D23Rik; ADP-glucose receptor; ADPG-R; BDPLT8; Gi-coupled ADP receptor HORK3; G-protein coupled receptor SP1999; HORK3; P2RY12; P2T(AC); P2Y purinoceptor 12; P2Y(12)R; P2Y(AC); P2Y(ADP); P2Y(cyc); P2y12; P2Y12 platelet ADP receptor; P2YR12; purinergic receptor P2RY12; purinergic receptor P2Y, G-protein coupled 12; purinergic receptor P2Y, G-protein coupled, 12; purinergic receptor P2Y12; putative G-protein coupled receptor; SP1999
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 64805
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid