p300 Monoclonal Antibody (NM11), Active Motif™

Mouse Monoclonal Antibody

Supplier:  Active Motif 61401

Catalog No. 50-199-3370

Description

EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.

Specifications

• Antigen: p300
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
• Gene Accession No.: Q09472
• Gene Symbols: EP300
• Immunogen: The antibody was raised against full-length p300 purified from human 293 cells.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ChIP Assay, ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence
• Clone: NM11
• Conjugate: Unconjugated
• Gene: EP300
• Gene Alias: A430090G16; A730011L11; E1A binding protein p300; E1A-associated protein p300; E1A-binding protein, 300kD; EP300; Histone acetyltransferase p300; Histone butyryltransferase p300; Histone crotonyltransferase p300; KAT3B; P300; p300 HAT; Protein propionyltransferase p300; RSTS2
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2033
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid