Invitrogen™ p300 Monoclonal Antibody (RW128)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA116608

Catalog No. PIMA116608

Description

Suggested positive control: HeLa nuclear extract.

EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.

Specifications

• Antigen: p300
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: B2RWS6, Q09472
• Gene Symbols: EP300
• Immunogen: Fusion protein containing residues 1572-2371 of human p300.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey, Mustelid
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Flow Cytometry, Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: RW128
• Conjugate: Unconjugated
• Gene: EP300
• Gene Alias: A430090G16; A730011L11; E1A binding protein p300; E1A-associated protein p300; E1A-binding protein, 300kD; Ep300; Histone acetyltransferase p300; Histone butyryltransferase p300; Histone crotonyltransferase p300; KAT3B; P300; p300 HAT; Protein propionyltransferase p300; RSTS2
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 170915, 2033, 328572
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid